Self-Mutilation & Rage Paxil & Zoloft 15/12/2002 U.S.A. 17 Year Old Girl Exhibits Bizzare Behavior on Meds
Summary:
http://www.fda.gov/ohrms/dockets/ac/04/transcripts/2004-4065T1.htm
MS. WEBB: I
am here because three years
ago my daughter was suffering some symptoms that
the doctor felt represented depression and started
her on samples of Paxil. I trusted this decision
as a mother and based on my medical background as a
registered nurse.
Unfortunately, she did have an obvious
worsening of symptoms. Were we aware that the
antidepressant could be the cause of this? No, we
were not. I am here because I agree that the FDA
needs to require further studies to be done to see
if it is true that certain antidepressants increase
the risk of suicidality.
When I learned that I would have the
opportunity to speak before this committee I wasn't
sure what I would say. So, I replayed an audiotape
of a confrontation with my then 17 year-old
daughter during the time she was taking these
antidepressants. We could not believe the changes
we saw in our daughter in the very short time she
had started on the antidepressants. It was
unbelievable--the rage, anger, the hostility she
exhibited that night. She ended the night by
cutting her wrist. Now I am learning that the
changes we saw in our daughter, more likely than
not, were the side effects of the antidepressant
she was taking at the time.
Yes, we did report a worsening of symptoms
shortly after she started the Paxil. The doctors
only changed her to another antidepressant, Zoloft.
She then continued to worsen and they continued to
increase the dosage until she began to further harm
herself with self-mutilation, cutting, overdose,
numerous things. We were fortunate to get her help
in the right environment with counselors who spent
many hours with the children. She was taken off of
the strong antidepressants and, within a short time
none of the staff could believe she had done while
she had been on Paxil and Zoloft. She continued
there, getting counseling, and returned as the
child we knew before she took these
antidepressants.
Why did we not know about these adverse
side effects that are now being reported in
children? Was it possible the drug companies may
have been aware of these adverse side effect? If
we had known, I believe it is possible that maybe
my daughter and our family would not have had to go
through the agony and heartache we went through.
My daughter is hearing impaired and has a
cochlear implant, and has worked hard all her life
to overcome the stigma of being hearing impaired
and deaf. It has been hard but she has always had
a positive attitude. Now we are sad but also find
relief in telling her that what she went through
could have been prevented if the drug companies had
made public these adverse side effects. Yes,
relief but, unfortunately, too late. She now has
to endure the stigma that mental illness brings to
those who suffer it. Luckily, she has shown her
determination to overcome this, as she did her
hearing loss. She is now a junior in college and
doing great. Her determination has brought her
through many obstacles but this was one she should
not have had to battle.
Guidelines for the use of antidepressants
in children should be reevaluated and studies done
to determine which, if any, are safe for use in
children. Thank God, we were able to get my
daughter help before it was too late. I am sure
there are many more children who did not get that
help and may have succeeded in their suicide
attempts. Thank you.