Mania & Psychosis Antidepressants 02/02/2004 U.S.A. ++200,000 a Year Enter Hospital Due to Antidepressant- Induced Mania/ Psychosis: FDA Testimony
Mania & Psychosis | Antidepressants | 2004-02-02 | U.S.A. | ++200,000 a Year Enter Hospital Due to Antidepressant- Induced Mania/ Psychosis: FDA Testimony |
Journal Article reference is from the Journal of Clinical Psychiatry 2001: 62: 30-33 titled: Antidepressant-Associated Mania and Psychosis Resulting in Psychiatric Admissions by Adrian Preda, M.D.; Rebecca W. MacLean, M.D.; Carolyn M. Mazure, Ph.D.; and Malcolm B. Bowers, Jr., M.D.
http://www.fda.gov/ohrms/dockets/AC/04/transcripts/4006T1.doc
DR. RUDORFER: Thank you. We are up to speaker 20.
Rosie Carr Meysenburg
MS. MEYSENBURG: My name is Rosie Carr
Meysenburg. I am from Dallas, Texas. I have no
financial ties with anybody but my husband of 40
years.
In my handout, I have highlighted what I
am speaking about here.
The first paper is a personal letter from
Dr. Peter S. Jensen. At that time, he was the head
of Child & Adolescent Disorders Research Branch of
the NIMH, the National Institute of Mental Health.
He said that research indicates that
antidepressants for depressed adolescents are not
very effective.
The second paper is a personal letter from
Dr. Larry S. Goldman, Director of the AMA, the
American Medical Association. He writes physicians
have known for many years the dangers of giving any
antidepressant to patients with certain disorders.
There is a substantial risk of precipitating mania
or psychosis.
The last item is a journal article from
the Journal of Clinical Psychiatry researched at
Yale University. It states that 11 percent of all
psychiatric hospital admissions were from
antidepressant-induced mania and psychosis.
It also states another area of research
that would be relevant to this issue is the work of
Winter and colleagues showing that Prozac and other
SSRIs can simulate the effects of LSD. In other
words, this is saying for some people, taking an
SSRI is the same as taking LSD.
About two million people enter a
psychiatric hospital every year, 11 percent then is
over 200,000 people a year who have an
antidepressant-induced psychosis and who are
hospitalized. Not all are hospitalized. Some of
them have either committed suicide, a homicide, or
a murder/suicide.